The Use of MR-Guided Radiation Therapy for Liver Cancer

Sabrina Prime; Joshua P Schiff; Ali Hosni; Teodor Stanescu; Laura A Dawson; Lauren E Henke

doi:10.1016/j.semradonc.2023.10.006

The Use of MR-Guided Radiation Therapy for Liver Cancer

Semin Radiat Oncol. 2024 Jan;34(1):36-44. doi: 10.1016/j.semradonc.2023.10.006.

Authors

Sabrina Prime¹, Joshua P Schiff¹, Ali Hosni², Teodor Stanescu², Laura A Dawson², Lauren E Henke³

Affiliations

¹ Washington University School of Medicine in St. Louis, Department of Radiation Oncology, St. Louis, MO.
² Radiation Medicine Program, Princess Margaret Cancer Centre, Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.
³ University Hospitals/Case Western Reserve University, Department of Radiation Oncology, Cleveland, OH. Electronic address: lauren.henke@uhhospitals.org.

PMID: 38105091
DOI: 10.1016/j.semradonc.2023.10.006

Abstract

The role of radiotherapy in the management of primary and metastatic liver malignancies has expanded in recent years due to advances such as IGRT and SBRT. MRI-guided radiotherapy (MRgRT) has arisen as an excellent option for the management of hepatocellular carcinoma, cholangiocarcinoma, and liver metastases due to the ability to combine improved hepatic imaging with conformal treatment planning paradigms like adaptive radiotherapy and advanced motion management techniques. Herein we review the data for MRgRT for liver malignancies, as well as describe workflow and technical considerations for the 2 commercially available MRgRT delivery platforms.

Publication types

Review

MeSH terms

Humans
Liver Neoplasms* / diagnostic imaging
Liver Neoplasms* / radiotherapy
Magnetic Resonance Imaging / methods
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods
Radiotherapy, Image-Guided* / methods