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Meet Aurora TX from RedShiftBio

Thermal Ramping Characterization Solution

Meet Aurora TX from RedShiftBio

Gain more insights into your precious samples

  • 50 microliters of sample at 0.1 mg/mL is all you need for highly reproducible data.

The secondary structure characterization tool for all your applications

  • Characterize the structure of a wide range of biomolecules including RNA, LNPs, proteins, peptides, antibodies, ADCs, AAVs, and beyond by measuring change in stability due to buffer/pH/formulation, stress, point mutations, binding, and storage time/conditions.
  • Save time and money by collecting spectral data, under experimentally/therapeutically relevant conditions; no need to buffer exchange or dilute prior to measuring.
  • Thermal ramping applies stress in a repeatable and automated fashion to induce structural change and guide decision-making and candidate ranking, saving valuable R&D time.

Benchtop-friendly Design

  • Space-saving, all-in-one analytical unit with integrated touchscreen.
  • Intuitive user interface provides at-a-glance-determination of run status.
  • Streamlined optional buffer station enhances throughput by integrating up to 8 buffers directly into the system during analysis.

Complete automation from sample analysis to data processing

  • Reduce user error with minimal sample manipulations.
  • Monitor the critical relationship between structure and function in less time, with higher-quality data.
  • Full automation minimizes training and removes the need for dedicated super users.
  • No spectroscopy expertise required to interpret results- delta software analyzes the data and provides meaningful conclusions.
Meet Aurora TX from RedShiftBio

Discover Aurora TX for unparalleled insights into the structure and stability of RNA, Proteins and beyond.

Download our brochure today!

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Redshiftbio

Meet Aurora TX from RedShiftBio

Thermal Ramping Characterization Solution

Thermal Ramping Characterization Solution

Gain more insights into your precious samples

  • 50 microliters of sample at 0.1 mg/mL is all you need for highly reproducible data.

The secondary structure characterization tool for all your applications

  • Characterize the structure of a wide range of biomolecules including RNA, LNPs, proteins, peptides, antibodies, ADCs, AAVs, and beyond by measuring change in stability due to buffer/pH/formulation, stress, point mutations, binding, and storage time/conditions.
  • Save time and money by collecting spectral data, under experimentally/therapeutically relevant conditions; no need to buffer exchange or dilute prior to measuring.
  • Thermal ramping applies stress in a repeatable and automated fashion to induce structural change and guide decision-making and candidate ranking, saving valuable R&D time.

Benchtop-friendly Design

  • Space-saving, all-in-one analytical unit with integrated touchscreen.
  • Intuitive user interface provides at-a-glance-determination of run status.
  • Streamlined optional buffer station enhances throughput by integrating up to 8 buffers directly into the system during analysis.

Complete automation from sample analysis to data processing

  • Reduce user error with minimal sample manipulations.
  • Monitor the critical relationship between structure and function in less time, with higher-quality data.
  • Full automation minimizes training and removes the need for dedicated super users.
  • No spectroscopy expertise required to interpret results- delta software analyzes the data and provides meaningful conclusions.
Meet Aurora TX from RedShiftBio
RNA and LNP analysis with Aurora TX

RNA and LNP analysis with Aurora TX

Aurora TX, powered by Microfluidic Modulation Spectroscopy (MMS), presents a pioneering strategy for RNA structure analysis. Aurora TX makes analyzing RNA structure a breeze, utilizing nearly drift-free, background compensated scans of the Amide I band (1700-1600 cm-1), typically used on proteins, but also ideal for nucleic acid characterization. Unlike conventional methods, Aurora TX provides unparalleled sensitivity and precision, effortlessly overcoming challenges of traditional spectroscopic techniques, such as manual workflows, buffer interference and background subtraction. This enables easy detection and comparison of RNA changes that are vital for therapeutic development.

Our MMS technology also boasts the capability to deliver multiple measurements in a single analysis, unveiling a wealth of insights including structural changes, stability, concentration variations, and RNA to LNP ratio, all with walk-away automation. Furthermore, robust delta software offers you an uncomplicated approach to RNA structural data collection and interpretation of results.

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